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Effect of Intravenous Infusion of Magnesium Sulfate on Opioid Use to Reduce Pain After Laparotomy in Patients with a History of Radiotherapy. 3 https://doi.org/10.58209/gmjm.2.2.67
URL: http://daneshafarand.org/article-1-188-en.html
Abstract:   (1855 Views)
Aims: Due to the adverse effects of injectable opioids after surgery and the suggestions of many researchers to find a reliable way to replace opioid use and also the contradictory results of the most appropriate method of using magnesium sulfate to control and reduce postoperative pain, this study was to evaluate the effect of intravenous infusion of magnesium sulfate on opioid use on reduce pain after laparotomy in patients with a history of radiotherapy.
Instrument & Methods: In this descriptive cross-sectional study, 50mg/kg of bolus magnesium sulfate was injected before surgery; then, after the end of surgery, 500mg/hr of the same drug was injected. Pain intensity was assessed in patients in two different groups.
Findings: No statistically significant relationship was observed in the hemodynamic status of patients in both groups before, during and after surgery. The rate of drug use in the intervention group was associated with a decrease over time, while no significant reduction was seen in the control group. Also, no statistically significant relationship was observed between the two groups after surgery.
Conclusion: Using magnesium sulfate, although it is effective in reducing the need for opioids in laparotomy patients with a history of radiotherapy, but can not reduce the need for opioids to zero.
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Article Type: Descriptive & Survey | Subject: Biotechnology

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