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Continuous Moderate-Intensity Exercise: Effects on Diabetic Ulcers in Type 2 Diabetes Mellitus. 3
URL: http://daneshafarand.org/article-1-61740-en.html
URL: http://daneshafarand.org/article-1-61740-en.html
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Introduction
Diabetes mellitus (DM) is a group of metabolic diseases marked by hyperglycemia that primarily endangers human health in the twenty-first century. Type 2 Diabetes Mellitus (T2DM) is caused by defects in insulin secretion, insulin action, or both, and accounts for 90-95% of all types of diabetes. According to data on the incidence of diabetes mellitus, 537 million adults (20-79 years) have diabetes; this figure is expected to rise to 643 million by 2030 and 783 million by 2045[1] . According to Riskesdas 2018, the prevalence of diabetes mellitus in Indonesia in 2007 was 5.7 percent, then rose to 6.9% in 2013, and then rose again to 8.5% in 2018 [2].
The most serious complication of diabetes mellitus is Diabetic Foot Ulcer (DFU). DFU occurs in diabetic patients, accounting for nearly 25% of all diabetic patients[3–5] . During the course of the disease, DFU accounts for 14 to 24% of lower extremity amputations [6] . DFU develops as a result of peripheral neuropathy, ischemia, and neuro-ischemia. The loss of protective sensation and muscle coordination in the feet caused by neuropathy affects mechanical stresses during ambulation [7, 8] . Furthermore, the decreased oxygen supply in the lower limb causes ischemia and can result in a wound.
DFU can be caused by a combination of ischemia and neuropathy, both of which deteriorate the patient's skin integrity. DFU is a DM complication that can be treated. Appropriate dietary, activity, and therapy changes can all have an impact on DFU healing. DFU will heal at a rate of 60-80%. However, 10-15% will remain germinate, and 5-24% will have an amputation within 6-18 months
Diabetes mellitus (DM) is a group of metabolic diseases marked by hyperglycemia that primarily endangers human health in the twenty-first century. Type 2 Diabetes Mellitus (T2DM) is caused by defects in insulin secretion, insulin action, or both, and accounts for 90-95% of all types of diabetes. According to data on the incidence of diabetes mellitus, 537 million adults (20-79 years) have diabetes; this figure is expected to rise to 643 million by 2030 and 783 million by 2045
The most serious complication of diabetes mellitus is Diabetic Foot Ulcer (DFU). DFU occurs in diabetic patients, accounting for nearly 25% of all diabetic patients
DFU can be caused by a combination of ischemia and neuropathy, both of which deteriorate the patient's skin integrity. DFU is a DM complication that can be treated. Appropriate dietary, activity, and therapy changes can all have an impact on DFU healing. DFU will heal at a rate of 60-80%. However, 10-15% will remain germinate, and 5-24% will have an amputation within 6-18 months
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