Volume -
3 , - : 127-131 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Relationship between Novel Markers and Sperm Quality in Obese Rats. 3 https://doi.org/10.58209/gmjm.3.4.127
URL: http://daneshafarand.org/article-1-237-en.html
URL: http://daneshafarand.org/article-1-237-en.html
Abstract: (596 Views)
Aims: Obesity and inflammation, which result from obesity, affect fertility and the male reproductive system by negatively affecting erectile dysfunction and semen variables. Novel factors could be used to determine fertility and infertility. This study was conducted to evaluate the relation between novel markers and sperm quality in obese rats.
Materials & Methods: The animals were divided into two groups. One group received a normal rat pellet diet for 12 weeks of intervention, while the other received a high-fat diet. The serum concentrations of IL-1β, IL-6, IL-3, TNF-α, sialic acid, CRP, haptoglobin, and fibrinogen were measured. Sperm motility was assessed.
Findings: Progressive motility, non-progressive motility, and immotile were respectively lower and higher in obese rats compared to control groups (P<0.05). It was observed that there was a positive correlation between inflammatory factors and immobility and a negative correlation between progressive motility and inflammation (P<0.05).
Conclusion: Pro-inflammatory factors have a significant correlation with sperm quality and could be used as markers for infertility.
Materials & Methods: The animals were divided into two groups. One group received a normal rat pellet diet for 12 weeks of intervention, while the other received a high-fat diet. The serum concentrations of IL-1β, IL-6, IL-3, TNF-α, sialic acid, CRP, haptoglobin, and fibrinogen were measured. Sperm motility was assessed.
Findings: Progressive motility, non-progressive motility, and immotile were respectively lower and higher in obese rats compared to control groups (P<0.05). It was observed that there was a positive correlation between inflammatory factors and immobility and a negative correlation between progressive motility and inflammation (P<0.05).
Conclusion: Pro-inflammatory factors have a significant correlation with sperm quality and could be used as markers for infertility.
Article Type: Original Research |
Subject:
Biotechnology
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |