Aims: Post-traumatic stress disorder is an anxiolytic disorder which is occurred following exposure to incidents followed by damage or threat. The aim of this study was to assess the effect of having a post-traumatic stress disorder man on the quality of life, depression, stress, anxiety and structure of the family.

Materials & Methods: This cross-sectional comparative study was done on the families referred to Shiraz Jannat Hospital in 2011-12. 100 families having PTSD man and 100 normal families were selected using achievable sampling method. Data collected by quality of life questionnaire, depression, anxiety and stress questionnaire, and agreeableness and family cohesion scale completed ​​by man, their spouses and children over the 18 years old. Data analyzed by SPSS 18 and Independent-T test.

Findings: Physical health, mental health and environmental health domains of men in PTSD group were significantly less than men in control group, but a significant difference only was observed in mental health scores between two groups. Depression and stress in men and families of PTSD group were significantly higher than men and families of control group. Men and families of PTSD group performed weaker compared to men and families in control group in the cohesion and adaptability domains.

Conclusion: Families having husband with PTSD have poor condition in the structural and emotional and generally in quality of life domains compared to the families without husband with PTSD.